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(2020) 36:e3213

10.1093/humrep/den060 24

Collectively, these findings suggest that IIR potentiates the insulin-sensitizing effect of exercise by enhancing blood flow, which increases glucose delivery to the prior ischemic-reperfused muscle

Bela et al., 2022)

Subsequent mass spectrometry-based studies consistently found that a range of NRF2-activating compounds are able to covalently modify Cys151, Cys273, and Cys288, confirming their importance in the KEAP1-mediated stress response, as well as identifying other sensor residues, including Cys226 (111114)