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Detection of intact TB-500 and several metabolites has been achieved in equine urine and plasma samples

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This 15-amino acid peptide, derived from a naturally occurring protein in human gastric juice, has been the subject of over 100 peer-reviewed studies spanning more than three decades

[DOI] [PMC free article] [PubMed] [Google Scholar] 70.Hirsch E.C., Graybiel A.M., Duyckaerts C., Javoy-Agid F

In ALS, there is an abnormal cytoplasmic aggregation of misfolded proteins, mainly DNA-binding protein 43 (TDP-43), and fused in sarcoma (FUS) (Wijesekera and Leigh 2009)
