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Bilirubin-induced PPAR signaling may be the reason for the significantly lower body mass index (BMI), glucose, and insulin levels observed in these individuals [55,56]

Glutathione works by donating electrons to neutralize reactive oxygen species (ROS) generated during alcohol metabolism, preventing the lipid peroxidation and mitochondrial damage that manifest as fatigue and brain fog

Continuing their work on MSC-based treatments of PD, Sun et al

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Pro-inflammatory cytokines (e.g., TNF- and IL-6) and M1 macrophages markers (e.g., CD11c) were significantly increased in the livers of hyperglycemic mice expressing hepatocyte-specific glycerol-3-phosphate phosphatase (G3PP) that hydrolyzes glycerol-3-phosphate (Gro3P) to glycerol [121]