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The Impact of Serine Metabolism on Aging The metabolic pathways involving Serine exert profound influence on age-related biological changes, particularly regarding homeostatic cellular mechanisms, protection against oxidative damage, and genomic integrity maintenance

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Cao FB, Cai Y, Liu L, Zhang M, He XY, Zhang GP et al (2015) Differences in photosynthesis, yield and grain cadmium accumulation as affected by exogenous cadmium and glutathione in the two rice genotypes

TRPV2 belongs to the TRPV subfamily of transient receptor potential (TRP) channel families and plays a critical role in promoting calcium influx

Hypoxia not only causes the accumulation of immunosuppressive metabolites (such as adenosine and lactic acid) in solid tumors, but also restricts the infiltration of immune cells, thus inhibiting the bodys anti-tumor immune responses

Conversely, IGF-1/IGF-2 ligand-neutralizing mAbs inhibit proliferative/anti-apoptotic signaling via IGF-1R and INSR-A, without compromising the metabolic function of INSR-B