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As described above, Ser345 is a target during priming of PMNs and for Pin1 binding

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10.1016/j.jnutbio.2011.01.001 37

Fibrosis and cirrhosis, outcomes of a continual process involving liver inflammation, destruction, and regeneration, mark advanced stages of chronic liver disease

reported that mice experiencing 2-h restraint stress (RS) during the light (inactive) phase (RS mice) had disrupted rhythms of Bmal1 and Per2 and a shift forward in the peak time of Rev-erb , resulting in abolished diurnal differences in urine volume voided per micturition 38