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Initial effects typically manifest within the first week

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Tendon and Ligament Repair Moderate to Strong Evidence Evidence Rating: Moderate-Strong (Several animal studies, some independent replication) Research support for musculoskeletal healing is substantial: Achilles tendon injuries Ligament damage (MCL, ACL) Rotator cuff healing General tendinopathy Surgical repair enhancement The FAK-paxillin mechanism and VEGF upregulation provide clear biological rationale for these effects

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MUC1, a glycoprotein naturally occurring on the surface of ductal epithelial cells, undergoes significant alterations during malignant transformation, including loss of polarization and overexpression in a hypoglycosylated form (Nath and Mukherjee, 2014)