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A number of mechanisms have been proposed to contribute to the cancer-promoting effects of choline deficiency: (1) enhanced liver cell regeneration and tissue sensitivity to chemical insults

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[DOI] [PMC free article] [PubMed] [Google Scholar] 42.Geraghty RJ, Krummenacher C, Cohen GH, Eisenberg RJ, Spear PG

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The heterogeneity of the clinical pictures of FM may suggest that different pathophysiological mechanisms, including immune and inflammatory factors, genetic predisposition to small fiber impairments, and mechanisms of central sensitization phenomena, together with psychiatric comorbidities, contribute to the clinical picture of FM [5]