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Desensitization of OR is studied on different signaling pathways including ACase inhibition, activation of MAP kinases, inhibition of voltage-gated calcium channels and activation of GIRK channels
To achieve homeostasis, too much is often as bad as too little in what is a very complex mechanism that necessitates fine control for optimum function

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Organic combination of the IVD and stem cell technology has outstanding advantages for IDD treatment and recovery, but remains controversial [10,11,12]
