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Its low molecular weight enables distribution throughout the bloodstream, reaching multiple tissues simultaneously

Regular or heavy alcohol consumption can interfere with the body's ability to absorb Vitamin B12 from the gut, making the supplement less effective

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Newer research compounds like retatrutide and MOTS-c have also come up in Rogan-adjacent episodes featuring guests like Derek (More Plates More Dates)

As we age, our levels of stomach acid start to decline, and these reduced levels can make it harder for B12 to be absorbed from food

Vitamin B12 helps form red blood cells and improves the nervous system and metabolism