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A study published in the Journal of Physiology found that carnitine supplementation elevated pyruvate dehydrogenase (PDH) flux and enhanced tissue metabolic flexibility

[DOI] [PMC free article] [PubMed] [Google Scholar] 5.OFlaherty C

3.2 L-carnitine levels in preterm infants Due to the large transfer of maternal L-carnitine to the fetus in the third trimester and the immature mechanism of carnitine transport in premature infants, the blood level of l-carnitine in premature infants after 3 to 7 days is slightly higher than that in full-term infants (5)

Chen et al., 2009

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These cofactors support the homocysteine clearance pathway that's temporarily overwhelmed by elevated methionine