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In the first part of this review, we summarize the current understanding of the immunological mechanisms in ALD by discussing immune response triggers (such as enteric dysbiosis, hepatocyte death and adipose-liver organ crosstalk) and immune response courses, including multiple immune cell types, major immune pathways, and specific immune mediators

We identified four main brain health benefits, which are memory booster, neuroprotective effect, anti-stress, and anti-nociceptive potentials with the proposed underlying mechanism

Rarely, long-term use might interfere with natural melanin production

The inhibitory effects of Riv on PAR-2-induced vascular inflammation may be involved, but whether there is a relationship between PAR-2 signaling and the Ang II type 1 receptor (AT 1 R) in blood pressure regulation has not been elucidated

doi: 10.1097/MIB.0b013e318289e17b

10.1016/j.envpol.2023.123013 [DOI] [PubMed] [Google Scholar] Huang D, Jiang Y, Zhao K, Qin F, Yuan Y, Xia B, Jiang G (2025a) Synergistic transformation of Cr (VI) in lubricant degradation by bacterial consortium