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It means that the efficacy of monotherapy could be offset by other signaling pathways

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Se ha visto que otras fuentes, particularmente de China, contienen contaminantes como diaciandiamida, dihidrotriazina, sulfato de dimetilo, tiourea, creatinina y/o concentraciones elevadas de metales pesados como mercurio y plomo debido al uso de diferentes precursores qumicos, procesos de sntesis mal controlados, uso de solventes orgnicos y/o mtodos de filtracin menos adecuados que aumentan la concentracin de estos contaminantes

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Mice with epidermal PGC-1 deletion showed lower level of cell differentiation via its regulation of cellular NAD + [12]

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showed that TMAO not only promoted cellular inflammation but also accounted for oxidative stress, thus playing an indirect role in promoting expression of inflammatory cytokines (74)

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