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Thus, mitochondrial dysfunction may play a role in the immune cell infiltration and inflamed microenvironment of pSS, increasing the oxidative stress and resulting in SG fibrosis

Evidence thatselenoproteins may be encoded in the +1 reading frameoverlapping the human CD4, CD8, and HLA-DR genes

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Biomaterials 51 , 238249 (2015)

Computational models Although computational models are currently less extensively applied in this field, they provide valuable predictive insights