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The STEP 4 withdrawal trial demonstrated that continued Semaglutide therapy was needed to maintain weight loss, as patients switched to placebo regained weight over 48 weeks (Rubino et al., JAMA 2021
Scheen has no conflicts of interest to declare that may be relevant to the contents of this article
10.1016/j.bmc.2024.117899 6 AshinskyB
The short answer is yes, but there are also potential health risks associated with tirzepatide
Now restrict calorie intake and survival mode sets in, with increased lipolysis from adipose tissue
These early effects are modest and may not be distinguishable from placebo
