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The repeated failures of A-targeted therapies highlight the need for a paradigm shift toward multi-targeted treatment approaches that address tau pathology, neuroinflammation, oxidative stress, mitochondrial dysfunction, and synaptic degeneration

Efficacy and safety of transcutaneous electrical nerve stimulation (TENS) for acute and chronic pain in adults: a systematic review and meta-analysis of 381 studies (the meta-TENS study)

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