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After 10 days of treatment, 6 mice from each group (H 2 O pre-UC and BB pre-UC) were sacrificed in order to evaluate the effect of BB in healthy animals

For the efficacy-evaluable population, the group of patients treated with ALC showed a significantly greater reduction in pain, compared to the placebo group

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Cleavage of sterol regulatory element-binding proteins (SREBPs) at site-1 requires interaction with SREBP cleavage-activating protein

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