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Further SAR studies showed that special disposition of basic nitrogen atom at the 7-position was important to exert high PDE5 inhibition and specificity, with optimized methylpicolyl group as in 11 reaching -40-fold selectivity over PDE6 (IC50 = 0.22 nM) [58]

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Estimation of antiradical properties of antioxidants using DPPH assay: A critical review and results

doi: 10.3389/fpls.2020.568887

While specific nomenclatures have been proposed for some of these GRXs (Ziemann et al., 2009

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