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Several factors contribute to this imbalance
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J Biol Chem 279:4272642731 Jez JM, Cahoon RE, Chen S (2004) Arabidopsis thaliana glutamate-cysteine ligase: functional properties, kinetic mechanism, and regulation of activity
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Upon metabolism into SAMe, it donates its methyl group and is converted into S-adenosylhomocysteine (SAH)
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