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doi: 10.3390/biomedicines9070822

Real-world data splits the pattern by body type: leaner, non-diabetic users stop the drug more often and restart it less often than users with type 2 diabetes, while diabetic users regain less weight but lose more blood-sugar control

It augments the other B vitamins functions while also exhibiting its own metabolic enhancing properties such as proper red blood cell formation, neurological function, and DNA synthesis

Cobalamin is a highly active and complex molecule

The prevalence of B12 deficiency in those older than 60 years is between 10% and nearly 20%.7,8 Because multiple causes can coexist in elderly patients, including poor absorption, protracted metformin use, and reduced dietary intake, these patients have the greatest risk for B12 deficiency and should be carefully monitored for signs of deficiency
