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Description
Designed as a three-arm randomised, double-blind, placebo-controlled intervention trial, the ErgMS study will supplement participants with placebo, 5 or 30 mg/d ergothioneine for 12 weeks, taking measurements of metabolic syndrome risk factors, serum markers of oxidative stress (lipid peroxidation), inflammation, blood platelet function and liver function at baseline, and after 6 weeks and 12 weeks of supplementation (Reference Tian, Cioccoloni and Sier97)
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Acamprosate works by stabilizing disrupted neurotransmitter activity in the brain, specifically reducing excess glutamate signaling and improving GABA function

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Methods: We present a case from our institution

Rahimi-Movaghar, V., Rasouli, M.R., Vaccaro A.R.:JAMA 302: 2202-2203, 2009