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Nowadays, pretty healthy people can boost their wellness and energy levels from IV Vitamin Therapy

Variations in the MTHFR gene can affect how the body metabolises B vitamins, including B12

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"Dietary Reference Intakes for Japanese 2010: Water-Soluble Vitamins" Journal of Nutritional Science and Vitaminology 2013(59):S67S82

An optimum dosage has not been established

Adjustments depend on lab markers and how well your symptoms respond