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Using the backward stepwise method, variables that resulted in the largest increase in the AIC were sequentially removed from the full model until the optimal AIC was achieved (Supplementary Table S2)

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Purity and Stability of the Peptide: This is, without a doubt, one of the most overlooked variables

Bystander neuronal death assay To assess bystander death of immature neurons, induced by microglia following SA treatment, microglia were seeded in 96 well cultures plate (N9 at a density of 10,000 cells/well/100 l and primary microglia at a density of 60,000 cells/300 l)