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This pattern was further confirmed by PCR analysis (Fig

Chem Commun 12:649650 Kasparov S, Brezov V, Valko M et al (2005) Study of the oxidative stress in a rat model of chronic brain hypoperfusion

Large reports have shown mitochondrial dysfunction is closely related to the progression of kidney diseases (Galvan et al., 2017)

Over time, oxidative stress, genetics, and aging deplete these cells, leading to the familiar loss of pigment