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For example, it requires the activated Cys302 residue and Glu268 but does not require the presence of NAD(P) +

critically reviewed and corrected all versions of the manuscript: T.M., F.M., K.M

In addition, pan-Kla has been found to regulate Kmt2a gene transcription in the hippocampal tissue, potentially disrupting synaptic plasticity and affecting cognitive functions in mice, such as spatial exploration and memory, by altering synaptic protein expression [78]

doi: 10.1097/SLA.0000000000001691 65 XuYTangYLuJZhangWZhuYZhangSet al