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That regulatory gap has real consequences

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PMCID: PMC9010660

While preclinical studies suggest exosomes derived from young plasma can inhibit syn propagation and support neuronal health in PD models [304, 305], but challenges related to standardized production, targeted delivery, and immunogenicity remain to be addressed before clinical application

Results have also revealed that chondrocytes from Hfe-KO mice were more likely to develop OA-related phenotypic characteristics, such as upregulation of MMPs expression, decreased production of extracellular matrix, and decreased expression of aggrecan

The neurostimulation study showed that the action potentials were similar in the reinnervated and healthy groups, but not in the degenerated nerves of Group 2