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Pathologically, PD is characterized by the degeneration and loss of dopaminergic neurons within the substantia nigra pars compacta, accompanied by the formation of eosinophilic inclusion bodies known as Lewy bodies within the residual neurons

Las categoras clave de genes afectados incluyen: Genes de colgeno y matriz extracelular : GHK-Cu regul al alza genes responsables de la produccin de colgeno I, colgeno III y elastina, apoyando directamente la estructura de la piel y la reparacin de heridas

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