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Intramuscular administration of vitamin B12 is often preferred for its rapid improvement in patients with severe deficiency or severe neurological symptoms

Wang XL, Feng ST, Wang ZZ et al (2021) Parkin, an E3 ubiquitin ligase, plays an essential role in mitochondrial quality control in Parkinsons disease

Because safety data remains limited, patients should avoid extended cycles unless a qualified provider determines that continued use is appropriate.

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Chandra et al
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