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T2D is thought to be a complication of metabolic syndrome caused by disorders of energy utilization and storage [1] and characterized by insulin resistance and deficiency of insulin secretion [2]

Side effects are most common when you first start using the medication or increase the dose, and higher doses of both drugs can lead to a higher risk of side effects

Immediate-release (IR) nicotinic acid dissolves rapidly in the stomach, causing a massive spike in blood levels that almost universally triggers the uncomfortable prostaglandin-driven "niacin flush." This intense redness and itching lead to very high patient dropout rates

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