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No active skincare for 48 hours Avoid harsh skincare ingredients like retinol, acids, and exfoliants to prevent irritation

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Because the two share overlapping repair pathways, isolating the effect of the combination is also difficult to design cleanly

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National Library of Medicine Primary regulatory Jul 1, 2026 accessed Jul 1, 2026 ClinicalTrials.gov registry search for AOD-9604 clinical trials, including the Phase 2 obesity program by Metabolic Pharmaceuticals that failed to meet primary weight loss endpoints