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Systemic administration (injectable or oral), which is less common than topical use and not part of approved or standard applications, would theoretically carry different safety considerations requiring appropriate clinical evaluation, though limited research on parenteral administration in animals has suggested acceptable safety profiles at moderate doses

Most available studies focus on oral or topical glutathione supplementation rather than injectable forms

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Cyanocobalamin Injection is one popular option often prescribed to address B12 deficiency

All data were acquired with Clampex and analysed offline with Clampfit 11.2 (Molecular Devices, Sunnyvale CA, USA), Excel, and GraphPad

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