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Description

We designed a peptide inhibitor prototype, named p53 TAD PEP, comprising 16 amino acids corresponding to residues 4257 of the p53 TAD sequence (Figure

Detection and significance of intratumoral TGF- and HGF/c-MET heterogeneity in glioblastoma The findings of an inhibitory effect on HGF/c-MET by TGF- in vitro prompted us to validate an association between the two pathways in vivo using human glioblastoma specimens

Its mechanism of action involves binding to the HGF receptor, also known as c-Met

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