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The incidence of IBD has increased dramatically in both industrialized and developing countries, and people are now being diagnosed at an increasing age (Kapadia et al., 2025)

Metabolic abnormalities in the basal ganglia and cerebellum in bipolar disorder: a multi-modal MR study

GSSG [ F (1, 57) = 6.53, p = 0.01

This improvement, however short-lived, shows that metals and other toxins are at the root of many of the symptoms, and a multi-modality detoxification would likely produce a longer lasting recovery