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The literature review uncovers presentations beyond isolated dystonia, displaying a complex phenotype with neuropsychiatric symptoms, seizures, myoclonus, intellectual disability, and mineralisation of basal ganglia, thus enhancing our understanding of VPS16 related disorders

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As a result, PTK activity becomes dominant, leading to increased Band 3 phosphorylation, reduced deformability, and altered blood rheology

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SPAG5-AS1 inhibited autophagy and aggravated apoptosis of podocytes via SPAG5/AKT/mTOR pathway