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These factors may explain the lower incidence of RN associated with the neoadjuvant SRT approach (123)

When the body is already struggling with nutrient deficiencies like low vitamin B12 or iron, environmental and hormonal factors can intensify the issue

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Resealing: Ensure the butyl stopper and flip-off cap are properly closed after each use

Second, many available studies are characterized by small sample sizes or lack appropriate control groups, making it difficult to draw definitive conclusions about therapeutic efficacy and optimal treatment protocols