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Apart from upregulation of ABC transporter protein expression, the PI3K/Akt pathway augments the drug efflux ability of ABC transporters by accelerating aerobic glycolysis-mediated the energy supply (Sui et al., 2014

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Meanwhile, temperature up-shift is considered as one of the environmental stressors 24

Forthcoming Events Dorset B12d Support Group Meeting July 2026 When: Friday 10th July 2026 11.30am 1pm and the second Friday in the month at 11.30am - 1pm Where: The Angel Inn, 188 Ringwood Road Longham Dorset BH22 9AP Who: Open to anyone affected by B12 deficiency patients, family, and friends welcome