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At these wavelengths, light energy penetrates the skin and underlying tissue and interacts with cytochrome c oxidase a mitochondrial enzyme involved in ATP (cellular energy) production

Administration can occur simultaneously or separately based on convenience

Inositol: Categorized as a B-vitamin, it helps lower blood cholesterol and facilitates fat metabolism

Best published PK (Awosemo et al., 2021, rats): ~38% oral bioavailability, ~6 to 7 hr oral half-life

These include serious infection, uremia or renal failure, drugs with bone marrow suppression properties (e.g., chloramphenicol), or concurrent undiagnosed folic acid or iron deficiency anemia

In proof-of-concept studies, NNMT inhibitors (NNMTis) have demonstrated promise as potential treatments for obesity and obesity-related metabolic comorbidities (e.g., T2D, fatty liver) 8,9,13