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It helps protect cells from damage caused by free radicals. 2

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S-acetylglutathione has also been shown to decrease TNF-alpha, NF-kappa beta, and F-2 isoprostane.[4,9-12] Additionally, there is mounting evidence that intracellular glutathione levels in antigen-presenting cells (e.g macrophages) may influence the Th1/Th2 cytokine response pattern and promote a balanced immune reaction.*[10]

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Clinical manifestations commonly include abdominal pain, diarrhea (with or without hematochezia), and weight loss