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Scopoletin and pinocembrin, when encapsulated in polymeric micelles, exhibit urate-lowering effects by inhibiting xanthine oxidase activity and promoting uric acid excretion, respectively, while significantly improving renal injury protection (Zeng et al., 2020

For example, oxytocin has a half-life of typically about three minutes in the blood when given intravenously

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Even though normal urate and ascorbate concentrations prevent lipid peroxidation in plasma, H 2 O 2 causes lipid peroxidation, oxidizes urate in the methemoglobin environment, and damages the erythrocyte membrane [125]