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an antibody of that specifically binds to an EphA2 polypeptide comprises a VL CDR1 having the amino acid sequence of SEQ ID NOS.: 8, 18, 28, 38, 48, 58, or 68, and a VL CDR2 having the amino acid sequence of SEQ ID NOS.: 9, 19, 29, 39, 49, 59, or 69

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