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Revised Date: January 18, 2023 Recommendations and Topics Scope Key Recommendations Background Epidemiology Patient Risk Factors Associated with B 12 Deficiency Patient Risk Factors Associated with Folate Deficiency Prevention Diagnosis Management Ongoing Care References Resources Appendix A: Dietary sources of cobalamin Scope This guideline covers the primary care investigation and management of cobalamin (vitamin B 12 or simply B 12 ) and folate deficiency in adults

2013;2018:CD010391

The microbiome in respiratory medicine: current challenges and future perspectives

HIF- has three isoforms, HIF-1, HIF-2, and HIF-3

doi: 10.1152/ajpcell.00502.2008

Iron homeostasis is maintained by the coordinated regulation of these critical proteins ( 2.2 Abnormal iron regulation in tumors Although there is considerable variation between cancer types, the expression of proteins involved in iron uptake, storage, and export is consistently altered in tumors at the cellular level ( Iron metabolism varies significantly between normal, peripheral, and tumor tissues, reflecting the distinct regulatory mechanisms in cancer cells