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The tradeoff is reduced bioavailability compared to injection, but proper application technique can partially compensate

It provides PubMed/PMC links and avoids medical or therapeutic claims

Support the bodys natural healing processes, potentially accelerating recovery from exercise and minor injuries

doi: 10.1038/nature11465 104 BruewerMLuegeringAKucharzikTParkosCAMadaraJLHopkinsAMet al

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This is not like mixing a protein shake where close enough works fine