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Mutations in the AUH gene result in the extremely rare autosomal recessive disorder referred to as 3-methylglutaconic aciduria, type 1 (MGCA1)

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Also, clinical studies done on patients with cervical cancer using pelvic radiation explained that Firmicutes-Proteobacteria ratio (F/P) reflects the severity of radiation toxicity, where it showed that patients with chronic radiation enteritis exhibited a reduction in Firmicutes and an increase in Proteobacteria

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