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Decreased cardiomyocyte cross-sectional area compared to vehicle-treated TAC mice

Previous studies have reported that iron overload could promote synovial inflammation and synovial hyperplasia in joint diseases such as hemophilic arthropathy [110]

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In all reported GPX families, the tetramer GPX3 eliminates all complex hydroperoxides, circulates in plasma in addition to its roles in cytoplasmic and mitochondria, and is a major ROS scavenger in plasma (Nirgude and Choudhary, 2021)

[PubMed 4201309] 485

Calcein-AM/PI solution was added and incubated for 15 min, and the distribution of living and dead cells was observed and photographed using a DMI8 inverted fluorescence microscope ( n = 3)