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It is hence crucial to maintain a good level of vitamin D as it plays a role in the management of both the reproductive and metabolic disorders related to PCOS ( Figure 2 )

Lysosomes are reservoirs of iron, and can initiate ferroptosis Ferrostatins accumulate in lysosomes, but their lysosomal localization does not contribute to their ability to suppress ferroptosis induced by erastin or RSL3

CAR-HEMATOTOX: a model for CAR T-cell-related hematologic toxicity in relapsed/refractory large B-cell lymphoma

142 IGF-1 increases cellular senescence in VSMCs by inducing DNA damage and increasing ROS production via the p53 pathway

& Gahan, P

The activity of islet cells is closely associated with diabetes, and insufficient insulin secretion caused by pancreatic -cell failure contributes to hyperglycemia