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Seminars in oncology

Lactylation of lysine residues occurs not only on histones, but also on nonhistone proteins, such as METTL3, the writer of the RNA m6A modification, which promotes immunosuppression of tumor-infiltrating myeloid cells in colon cancer (22), and tumor suppressor TP53 (23)

& Armengaud, C

doi: 10.3892/ol.2020.11863

Coincident depletion of glutathione (GSH) or inactivation of glutathione peroxidase-4 (GPX4) leads to a newly characterized form of cell death, coined ferroptosis (Dixon et al., 2008)

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