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In addition, DMF treatment increased DNA 5hmC but not 5mC levels in the CBS gene promoter CpG island (Fig

C-D, Heatmaps of upregulated (A) or downregulated (B) genes in the three RNAseq biological repetitions (1,2,3) before and after high temperature shift

They found an inverse relation between tissue ascorbate level and HIF1 expression ( r = 0.288, p = .025)

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doi: 10.3390/molecules25102415

doi: 10.3390/cancers12061435 86 LiuJDingXTangJCaoYHuPZhouFet al