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To directly feed the heme-biosynthesis pathway, measure mitochondrial respiration, and trace metabolic flux in cellular and animal models
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But as you age, a sneaky enzyme called NNMT starts clogging up the works
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This can cause methyl trapping, where the excess methylfolate is unable to be utilised in the methionine cycle (through the MTR enzyme) as usable B12 levels are too low
