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Beyond cosmetic concerns, the potential anti-ageing effects of ergothioneine in the brain have also been of significant research interest, with in vivo data from animal models showing that ergothioneine protects neurons from damage by cisplatin (72) , -amyloid (73) , and age-related learning and memory deficits (74)

[23] did not show superior results in patients undergoing two infiltrations

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Lam CSP, Chen MH, Lacey SM, Yang Q, Sullivan LM, Xanthakis V, Safa R, Smith HM, Peng X, Sawyer DB, Vasan RS

And FDA regulators agreed, saying later that the substances "present significant safety risks," because most have not been extensively tested in humans