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Citrate synthase is encoded by the CS gene

CLIC1 undergoes a large conformation change upon oxidation

You do not want only synthesis without clearing damaged tissue, and you do not want only breakdown without rebuilding

For oral administration, clinical trials have studied doses ranging from 1-30 mg daily, with typical protocols using 1-2 mg per dose on an empty stomach

AD pathogenesis involves complex molecular and cellular mechanisms

This toxicity can lead to a predisposition to inflammatory (autoimmune) diseases including Alzheimers, MS, Parkinsonism, diabetes, chronic fatigue syndrome (CFS), chronic pain syndromes, cardiovascular misadventures, viral insult, cancers and rapid aging