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Such studies indicated that synovial lining fibroblasts (Thy1-) were found to be predominantly responsible for driving articular damage, whereas sub-lining layer fibroblasts (Thy1 +) are mainly pro-inflammatory [30]

This review systematically summarized the relationship between intestinal microenvironment and PSCI, and the role and potential mechanism of acupuncture in preventing and treating PSCI by regulating the intestinal microenvironment, trying to evaluate the role of intestinal microenvironment in the prevention and treatment of PSCI by acupuncture and its possible mechanism, so as to provide new ideas and targets for the research of traditional Chinese medicine in treating PSCI

elegans , PARP inhibition results in a significant lifespan extension in wild-type worms 190 , in a model of ataxia telangiectasia 135 and under hyperglycaemic conditions 221

Declining GH levels with age contribute to sarcopenia, increased body fat, and slower recovery